Which drug is also indicated for the treatment of obsessive-compulsive disorder among tricyclic antidepressants?

Which drug is also indicated for the treatment of obsessive-compulsive disorder among tricyclic antidepressants?

• A. Desipramine.
• B. Maprotiline.
• C. Clomipramine.
• D. Amoxapine.

Answer: (C)

Clomipramine is recognized for its effectiveness not only as a tricyclic antidepressant but also specifically for the treatment of obsessive-compulsive disorder (OCD). This is due to its potent serotonin reuptake inhibition, which plays a critical role in reducing the symptoms associated with OCD. While other tricyclic antidepressants like desipramine, maprotiline, and amoxapine may possess some antidepressant properties, they do not have the same level of efficacy established for OCD treatment as clomipramine. The distinct pharmacological profile of clomipramine, particularly its action on serotonin pathways, makes it a preferred choice for addressing the compulsive behaviors typical of OCD, in addition to its antidepressant qualities. Thus, clomipramine is the clear option among tricyclic antidepressants for treating this specific condition.

Clomipramine is recognized for its effectiveness not only as a tricyclic antidepressant but also specifically for the treatment of obsessive-compulsive disorder (OCD). This is due to its potent serotonin reuptake inhibition, which plays a critical role in reducing the symptoms associated with OCD.

While other tricyclic antidepressants like desipramine, maprotiline, and amoxapine may possess some antidepressant properties, they do not have the same level of efficacy established for OCD treatment as clomipramine. The distinct pharmacological profile of clomipramine, particularly its action on serotonin pathways, makes it a preferred choice for addressing the compulsive behaviors typical of OCD, in addition to its antidepressant qualities. Thus, clomipramine is the clear option among tricyclic antidepressants for treating this specific condition.