Which patient population requires careful screening before starting an antidepressant due to the potential for increased risk of suicide?

Which patient population requires careful screening before starting an antidepressant due to the potential for increased risk of suicide?

• A. Middle-aged adults
• B. Adolescents and young adults
• C. Elderly patients
• D. Pediatric patients under 12

Answer: (B)

Adolescents and young adults require careful screening before starting an antidepressant due to a notable increased risk of suicidal thoughts and behaviors associated with this age group. Extensive research, including studies and clinical trials, has indicated that individuals in this demographic—especially those aged 18 to 24—demonstrate a heightened sensitivity to certain antidepressants. This risk is particularly relevant during the initial treatment phase and when dosage changes occur. The potential for adverse effects such as increased suicidal ideation can stem from the neurodevelopmental aspects of this age group, where brain maturation is in process. Therefore, careful monitoring and counseling are essential before and during treatment with antidepressants in adolescents and young adults. While other populations, including the elderly and younger pediatric patients, may also have specific considerations regarding antidepressant therapy, the distinct concern for suicidal risk in adolescents and young adults has led to more stringent guidelines and recommendations for screening and monitoring in this age category.

Adolescents and young adults require careful screening before starting an antidepressant due to a notable increased risk of suicidal thoughts and behaviors associated with this age group. Extensive research, including studies and clinical trials, has indicated that individuals in this demographic—especially those aged 18 to 24—demonstrate a heightened sensitivity to certain antidepressants. This risk is particularly relevant during the initial treatment phase and when dosage changes occur.

The potential for adverse effects such as increased suicidal ideation can stem from the neurodevelopmental aspects of this age group, where brain maturation is in process. Therefore, careful monitoring and counseling are essential before and during treatment with antidepressants in adolescents and young adults.

While other populations, including the elderly and younger pediatric patients, may also have specific considerations regarding antidepressant therapy, the distinct concern for suicidal risk in adolescents and young adults has led to more stringent guidelines and recommendations for screening and monitoring in this age category.